Calcigen® D

Calcigen® D is a vitamin-mineral combination preparation consisting of calcium carbonate 1500 mg (corresponds to 600 mg calcium) and vitamin D3 (cholecalciferol) 400 I.U for twice daily intake. If the preparation is used during pregnancy, however, it may only be taken once a day at the most. It is only available from a pharmacy, but does not require a prescription and is supplied in the form of effervescent or chewable tablets.

operation area

Calcigen® D is combined to compensate Calcium- and Vitamin D3-Deficiencies or to prophylaxis such deficiencies are used. This is particularly important with the Osteoporosis prophylaxis and Osteoporosis treatment a role.

particularities while taking:

While taking Calcigen® D should periodically use the Kidney function can be checked by determining the creatinine level in the serum. In addition, a repetitive determination of Calcium level occur in serum and urine. This is especially important in patients who are simultaneously Cardiac glycosides and or Diuretics ingest and a advanced age exhibit. Enormous mindfulness is also involved in accompanying therapy Bisphosphonates, Sodium fluoride or Tetracyclines of necessity. If another preparation is taken which contains vitamin D3 (Cholecalciferol), the supplied Total dose of vitamin D3 (Cholecalciferol) get noticed. In patients who at Sarcoid (Boeck's disease), there is an increased change in vitamin D3 (cholecalciferol) towards its active metabolites. Here too, the calcium level in the blood and urine should be checked at regular intervals. Please inform your treating doctor if you have one Renal failure because the vitamin D3 (cholecalciferol) metabolism is disturbed here.

Adverse drug effects

Side effects which occur rarely, i.e. in 1 to 10 out of 10,000 patients, are:

• Hypersensitivity reactions (Hives, rashes),
• itching
• Eructation
• Bloating
• nausea and Vomit
• Flatulence, constipation, diarrhea
• increased levels of calcium in the blood (Hypercalcemia)
• increased calcium excretion on the urine (Hypercalcuria) and
• a increased feeling of thirst

With a long lasting Overdose of the preparation there is an increased risk of developing:

• calcium-containing kidney stones
• a headache
• Racing heart (Tachycardia)
• Cardiac arrhythmias
• Muscle, bone- and Joint pain

Interactions

It can too Interactions With diuretics (Thiazide-type diuretics such as hydrochlorothiazide) come which eventually become a Hypercalcemia can condition.

The effect of Vitamin D3 (Cholecalciferol) can be disturbed by the following drugs:

• Barbiturates
• Glucocorticoids
• Phenytoin and
• Rifampicin

When taking Cholestyramine against a Hypercholesterolemia (high blood cholesterol) should at least two hours distance between taking Calcigen® D and Cholestyramine must be observed, as otherwise the absorption of Calcigen® D in the gastrointestinal tract may be impaired. The absorption of iron can also be affected, which is why ferrous preparations two hours before or two hours to should be added to the intake of Calcigen® D. This two-hour interval also applies to the cytostatic agent estramustine. With certain antibiotics, such as tetracyclines or bisphosphonates and sodium fluoride, the interval should be at least three hours.

Since taking Calcigen® D results in a Increase in calcium levels can come in the blood, there is a possibility that the sensitivity across from Medicationthat at a Heart failure are used (cardiac glycosides) increased is and the risk for Cardiac arrhythmias increased is.

Also Interactions With Food are known. Food comes with me Oxalic acid (such as rhubarb, star fruits, chard, cocoa and many more), phytic acid (for example in corn, soy or peanut), Phosphates (e.g. in processed cheese or soft drinks) or those with a considerable fiber content.

pregnancy and breast feeding period

Calcigen® D can in the pregnancy and Lactation can be used to counteract a calcium and vitamin D3 (cholecalciferol) deficiency.

Please also read: Vitamins in Pregnancy

However, it is important that a maximum of one tablet per day is taken so that a daily dose of 1500 mg calcium and 600 I.E. vitamin D3 (cholecalciferol) is not exceeded. At the Breastfeeding it should be noted that calcium and vitamin D3 (cholecalciferol) in the Breast milk trespass. Calcigen® D is used by pregnant and breastfeeding women two hours before or after one meal consumed to take, otherwise the Iron absorption in the gastrointestinal tract with special needs can be.

Contraindications

Calcigen® D must not be part of their therapy plan if they are to Hypersensitivity reactions tend towards calcium carbonate, vitamin D3 (cholecalciferol) or other components of this vitamin and mineral preparation. In addition, it must not be with a increased calcium concentration in the blood (Hypercalcemia), one increased calcium excretion on the urine (Hypercalcuria) or one Long-term immobilization be taken with hypercalcemia and / or hypercalcuria.

Further Contraindications for therapy with Calcigen® D are Kidney stones, a Myeloma, which is a cancer of the bone marrow, Bone metastases and a primary Hyperparathyroidism (pHPT), so one Overactive parathyroid gland.

Attention should apply to the following ailments:

• Renal failuredecreased kidney function
• Kidney calcification
• a increased excretion from Calcium on the urine (Hypercalcuria) and
• at a lower phosphate concentration in the blood (Hypophosphatemia).

If you are unsure, you should definitely consult your doctor or pharmacist.